When Spanish colonial restrictions on Jewish settlement lifted in 1799, an enterprising group of Sephardic Jews from Curaçao seized the opportunity to establish new lives in Santo Domingo, fundamentally shaping Dominican society for generations to come. Through analysis of tombstone inscriptions, genealogical records, and correspondence between Dominican officials and Jewish organizations, this research traces the remarkable trajectory of these settlers and their descendants. The Sephardic immigrants quickly established themselves as prominent merchants and became instrumental in Dominican independence movements and national development. Despite widespread intermarriage with local Catholics and eventual religious conversion to Christianity, these families maintained a striking pride in their Jewish heritage, preserving traditional Sephardic surnames and cultural identity. Today, approximately twenty families continue to identify as "hebreos" and claim pure Sephardic lineage. Their enduring influence manifests through diplomatic, political, and commercial leadership, including consistent support for Jewish refugees and positive relations with Israel. The community's unique pattern of cultural assimilation combined with sustained ethnic pride illuminates broader patterns of Jewish diaspora communities throughout Latin America, demonstrating how religious transformation need not diminish ancestral identity.