The ancient Jewish concept of cross-generational retribution—where divine punishment for sins passes from parent to child—finds troubling new expression in modern genetic engineering. As humans gain unprecedented power to shape the genetic destiny of future generations, this capability may constitute a dangerous form of retribution driven by human arrogance rather than divine judgment. Through analysis of biblical and rabbinic sources, this theological investigation traces how Jewish thought has evolved from viewing cross-generational consequences as divine providence to understanding them as products of human free will, particularly following the Holocaust. The research synthesizes scientific critiques of genetic determinism by scholars like Richard Strohman and Paul Root Wolpe with Jewish theological perspectives on humans as partners with God in creation and tikkun olam (world repair). Drawing on philosophical and theological methodologies, the analysis reveals how genetic enhancement risks reducing children to mere artifacts while crossing fundamental boundaries of creation. These actions may represent a form of idolatry through human self-deification, visiting unforeseen punishments upon future generations in pursuit of genetic utopias. The findings emphasize the need to cultivate humility, modesty, and equity in exercising human freedom within appropriate limits of divine partnership.